Research

Contact Details

QBI Building, UQDI

Program in Complex Trait Genomics
Institute for Molecular Bioscience
306 Carmody Road
Building 80
The University of Queensland
St Lucia, QLD 4072
Australia

Email: a.mcrae [at] uq.edu.au

Group Website
 

Brief C.V.

Positions Held

  • NHMRC Career Development Fellow, Institute for Molecular Bioscience, The University of Queensland, 2016-.
  • Research Fellow, The Queensland Brain Institute, The University of Queensland, 2014-2016.
  • Visiting Scientist, QIMR Berghofer Medical Research Institute (Brisbane, Australia), 2012-2016.
  • Research Fellow, University of Queensland Diamantina Institute, The University of Queensland, 2012-2013.
  • Adjunct Lecturer, School of Biological Sciences, The University of Queensland (Brisbane, Australia), 2010-2013.
  • Research Officer, then Senior Research Officer, Queensland Institute of Medical Research (Brisbane, Australia), 2006-2011.
  • Research Associate, AgReseach (Invermay, New Zealand), 2002.

Education

  • PhD, University of Edinburgh, 2006. THESIS
  • BSc (Hons), Statistics and Genetics, University of Otago, 2002.

Research Support

  • National Health and Medical Research Council (NHMRC) Project Grant. Yang J and McRae AF. Methods and software tool for complex trait analyses using multi-omics data. 2015–2019.
  • Australian Research Council (ARC) Discover Project. Morris M, McRae AF, Youngson N. The importance of DNA methylation in response to environmental changes. 2016-2018.
  • National Health and Medical Research Council (NHMRC) Career Development Fellowship, 2015-2018.
  • National Health and Medical Research Council (NHMRC) Project Grant. Lind P, Whitfield J and McRae AF. Deep resequencing of Alcohol Dehydrogenases for alcohol use disorders and esophageal cancer. 2014-2016.
  • National Health and Medical Research Council (NHMRC) Project Grant. McRae AF and Painter JN. Inheritance of DNA methylation state in humans. 2011-2013.
  • National Health and Medical Research Council (NHRMC) Australian Based Biomedical Fellowship, 2008-2011.
  • Commonwealth Scholarship for PhD study, 2002-2005.

 

Publications

Google Scholar  –  ResearcherID  –  ORCID
 

  1. McRae AF, Marioni RE, Shah S, Yang J, Powell JE, Harris SE, Gibson J, Henders AK, Bowdler L, Painter JN, Murphy L, Martin NG, Starr JM, Wray NR, Deary IJ, Visscher PM, Montgomery GW. (2018) Identification of 55,000 replicated DNA methylation QTL. Scientific Reports 8: 17605.
  2. Zhang Q, Marioni RE, Robinson MR, Higham J, Sproul D, Wray NR, Deary IJ, McRae AF*, Visscher PM. (2018) Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine 10: 75 (* joint senior author)
  3. McCartney DL, Hillary RF, Stevenson AJ, Ritchie SJ, Walker RM, Zhang Q, Morris SW, Bermingham ML, Campbell A, Murray AD, Whalley HC, Gale CR, Porteous DJ, Haley CS, McRae AF, Wray NR, Visscher PM, McIntosh AM, Evans KL, Deary IJ, Marioni RE. (2018) Epigenetic prediction of complex traits and death. Genome Biology 19: 136
  4. Gerring ZF, McRae AF, Montgomery GW, Nyholt DR (2018) Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine. BMC Genomics 19: 69
  5. Wang Y, Karlsson R, Lampa E, Zhang Q, Hedman ÅK, Almgren M, Almqvist C, McRae AF, Marioni RE, Ingelsson E, Visscher PM, Deary IJ, Lind L, Morris T, Beck S, Pedersen NL, Hägg S. (2018) Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins. Epigenetics 13: 975-987
  6. Story Jovanova O, Nedeljkovic I, Spieler D, Walker RM, Liu C, Luciano M, Bressler J, Brody J, Drake AJ, Evans KL, Gondalia R, Kunze S, Kuhnel B, Lahti J, Lemaitre RN, Marioni RE, Swenson B, Himali JJ, Wu H, Li Y, McRae AF, Russ TC, Stewart J, Wang Z, Zhang G, Ladwig KH, Uitterlinden AG, Guo X, Peters A, Räikkönen K, Starr JM, Waldenberger M, Wray NR, Whitsel EA, Sotoodehnia N, Seshadri S, Porteous DJ, van Meurs J, Mosley TH, McIntosh AM, Mendelson MM, Levy D, Hou L, Eriksson JG, Fornage M, Deary IJ, Baccarelli A, Tiemeier H, Amin N. (2018) DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: Meta-analysis of multiethnic epigenome-wide studies. JAMA Psychiatry 75: 949-959.
  7. Fung JN, Mortlock S, Girling JE, Holdsworth-Carson SJ, Teh WT, Zhu Z, Lukowski SW, McKinnon BD, McRae AF, Yang J, Healey M, Powell JE, Rogers PAW, Montgomery GW. (2018) Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports 8: 11424
  8. Xue A, Wu Y, Zhu Z, Zhang F, Kemper KE, Zheng Z, Yengo L, Lloyd-Jones LR, Sidorenko J, Wu Y, eQTLGen Consortium, McRae AF, Visscher PM, Zeng J, Yang J. (2018) Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature communications 9: 2941
  9. Qi T, Wu Y, Zeng J, Zhang F, Xue A, Jiang L, Zhu Z, Kemper K, Yengo L, Zheng Z, eQTLGen Consortium, Marioni RE, Montgomery GW, Deary IJ, Wray NR, Visscher PM, McRae AF, Yang J (2018) Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature communications 9: 2282-2282
  10. Cuellar Partida G, Laurin C, Ring SM, Gaunt TR, McRae AF, Visscher PM, Montgomery GW, Martin NG, Hemani G, Suderman M, Relton CL, Davey Smith G, Evans DM (2018) Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics 27:2927-2939.
  11. Li S, Wong EM, Dugué PA, McRae AF, Kim E, Joo JE, Nguyen TL, Stone J, Dite GS, Armstrong NJ, Mather KA, Thalamuthu A, Wright MJ, Ames D, Milne RL, Craig JM, Saffery R, Montgomery GW, Song YM, Sung J, Spector TD, Sachdev PS, Giles GG, Southey MC, Hopper JL (2018) Genome-wide average DNA methylation is determined in utero. International Journal of Epidemiology 47: 908–916.
  12. Wu Y, Zeng J, Zhang F, Zhu Z, Qi T, Zheng Z, Lloyd-Jones LR, Marioni RE, Martin NG, Montgomery GW, Deary IJ, Wray NR, Visscher PM, McRae AF, Yang J. (2018) Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications 9: 918
  13. Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. (2018) GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications 9: 387
  14. Marioni RE, McRae AF*, Bressler J, Colicino E, Hannon E, Li S, Prada D, Smith JA, Trevisi L, Tsai PC, Vojinovic D, Simino J, Levy D, Liu C, Mendelson M, Satizabal CL, Yang Q, Jhun MA, Kardia SLR, Zhao W, Bandinelli S, Ferrucci L, Hernandez DG, Singleton AB, Harris SE, Starr JM, Kiel DP, McLean RR, Just AC, Schwartz J, Spiro A, Vokonas P, Amin N, Ikram MA, Uitterlinden AG, van Meurs JBJ, Spector TD, Steves C, Baccarelli AA, Bell JT, van Duijn CM, Fornage M, Hsu YH, Mill J, Mosley TH, Seshadri S, Deary IJ. (2018) Meta-analysis of epigenome-wide association studies of cognitive abilities. Molecular Psychiatry 23: 2133-2144(* joint first authors)
  15. Zeng J, de Vlaming R, Wu Y, Robinson MR, Lloyd-Jones LR, Yengo L, Yap CX, Xue A, Sidorenko J, McRae AF, Powell JE, Montgomery GW, Metspalu A, Esko T, Gibson G, Wray NR, Visscher PM, Yang J. (2018) Signatures of negative selection in the genetic architecture of human complex traits. Nature genetics 50: 746–753
  16. Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM. (2018) GWAS on family history of Alzheimer’s disease. Translational psychiatry 8: 99
  17. Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH Jr, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB; BIOS Consortium, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O’Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M. (2017) DNA methylation analysis identifies loci for blood pressure regulation. The American Journal of Human Genetics 101: 888-902
  18. Robins C, McRae AF, Powell JE, Wiener HW, Aslibekyan S, Kennedy EM, Absher DM, Arnett DK, Montgomery GW, Visscher PM, Cutler DJ, Conneely KN. (2017) Testing two evolutionary theories of human aging with DNA methylation data. Genetics 207: 1547-1560
  19. Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ, Buchwald J, Fiorito G, Ismail K, Iurato S, Joensuu A, Karell P, Kasela S, Lahti J, McRae AF, Mandaviya PR, Seppälä I, Wang Y, Baglietto L, Binder EB, Harris SE, Hodge AM, Horvath S, Hurme M, Johannesson M, Latvala A, Mather KA, Medland SE, Metspalu A, Milani L, Milne RL, Pattie A, Pedersen NL, Peters A, Polidoro S, Räikkönen K, Severi G, Starr JM, Stolk L, Waldenberger M, Eriksson JG, Esko T, Franke L, Gieger C, Giles GG, Hägg S, Jousilahti P, Kaprio J, Kähönen M, Lehtimäki T, Martin NG, van Meurs JBC, Ollikainen M, Perola M, Posthuma D, Raitakari OT, Sachdev PS, Taskesen E, Uitterlinden AG, Vineis P, Wijmenga C, Wright MJ, Relton C, Davey Smith G, Deary IJ, Koellinger PD, Benjamin DJ. (2017) An epigenome-wide association study meta-analysis of educational attainment. Molecular Psychiatry 22:1680-1690
  20. Mandaviya PR, Joehanes R, Aïssi D, Kühnel B, Marioni RE, Truong V, Stolk L, Beekman M, Bonder MJ, Franke L, Gieger C, Huan T, Ikram MA, Kunze S, Liang L, Lindemans J, Liu C, McRae AF, Mendelson MM, Müller-Nurasyid M, Peters A, Slagboom PE, Starr JM, Trégouët DA, Uitterlinden AG, van Greevenbroek MMJ, van Heemst D, van Iterson M, Wells PS, Yao C, Deary IJ, Gagnon F, Heijmans BT, Levy D, Morange PE, Waldenberger M, Heil SG, van Meurs JBJ. (2017) Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PloS One 12: e0182472.
  21. Garton FC, Benyamin B, Zhao Q, Liu Z, Gratten J, Henders AK, Zhang ZH, Edson J, Furlong S, Morgan S, Heggie S, Thorpe K, Pfluger C, Mather KA, Sachdev PS, McRae AF, Robinson MR, Shah S, Visscher PM, Mangelsdorf M, Henderson RD, Wray NR, McCombe PA. (2017) Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics & Genomic Medicine 5: 418-428.
  22. Elliott HR, Shihab HA, Lockett GA, Holloway JW, McRae AF, Davey Smith G, Ring SM, Gaunt TR, Relton CL. (2017) The Role of DNA Methylation in Type 2 Diabetes Aetiology–Using Genotype as a Causal Anchor. Diabetes db160874.
  23. Lloyd-Jones LR, Holloway A, McRae AF, Yang J, Small K, Zhao J, Zeng B, Bakshi A, Metspalu A, Dermitzakis M, Gibson G, Spector T, Montgomery G, Esko T, Visscher PM, Powell JE (2017) The genetic architecture of gene expression in peripheral blood. The American Journal of Human Genetics 100: 228-237.
  24. Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, Zhi D, Sandling JK, Yao C, Liu C, Liang L, Huan T, McRae AF, Demissie S, Shah S, Starr JM, Cupples LA, Deloukas P, Spector TD, Sundström J, Krauss RM, Arnett DK, Deary IJ, Lind L, Levy D, Ingelsson E. (2017) Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics 10: e001487.
  25. Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ. (2017) Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. PLoS Medicine 14: e1002215
  26. Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski K, Salfati EL, Fiorito G, Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao PS, Liu C, Zhao W, Guarrera S, Michopoulos VJ, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch H, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin D, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Starr JM, Visscher PM, Murabito JM, Kardia SLR, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Meurs JBJ, Franco OH, Chen YDI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinkle E, Koenig W, Arnett DK, Baccarelli AA, Benjamin EJ, Dehghan A. (2016) DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology 17: 255
  27. Kassam I, Lloyd-Jones L, Holloway A, Small KS, Zeng B, Bakshi A, Metspalu A, Gibson G, Spector TD, Esko T, Montgomery GW, Powell JE, Yang J, Visscher PM, McRae AF. (2016) Autosomal genetic control of human gene expression does not differ across the sexes. Genome Biology 17, 248
  28. Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, Almli LM, Zhi D, Wang Y, Huan T, Yao C, Mendelson MM, Joehanes R, Liang L, Love SA, Guan W, Shah S, McRae AF, Kretschmer A, Prokisch H, Strauch K, Peters A, Visscher PM, Wray NR, Guo X, Wiggins KL, Smith AK, Binder EB, Ressler KJ, Irvin MR, Absher DM, Hernandez D, Ferrucci L, Bandinelli S, Lohman K, Ding J, Trevisi L, Gustafsson S, Sandling JH, Stolk L, Uitterlinden AG, Yet I, Castillo-Fernandez JE, Spector TD, Schwartz JD, Vokonas P, Lind L, Li Y, Fornage M, Arnett DK, Wareham NJ, Sotoodehnia N, Ong KK, van Meurs JBJ, Conneely KN, Baccarelli AA, Deary IJ, Bell JT, North KE, Liu Y, Waldenberger M, London SJ, Ingelsson E, Levy D. (2016) A DNA methylation biomarker of alcohol consumption Molecular Psychiatry (in press)
  29. Kassam I, Qi T, Lloyd-Jones L, Holloway A, Bonder MJ, Henders AK, Martin NG, Powell JE, Franke L, Montgomery GW, Visscher PM, McRae AF (2016) Evidence for mitochondrial genetic control of autosomal gene expression. Human Molecular Genetics 25: 5332-5338.
  30. Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, Pankow JS, Kunze S, Shah S, McRae AF, Lohman K, Sha J, Absher DM, Ferrucci L, Zhao W, Demerath EW, Bressler J, Grove ML, Huan T, Liu C, Mendelson MM, Yao C, Kiel DP, Peters A, Wang-Sattler R, Visscher PM, Wray NR, Starr JM, Ding J, Rodriguez CJ, WarehamNJ , Irvin MR, Zhi D, Barrdahl M, Vineis P, Ambatipudi S, Uitterlinden AG, Hofman A, Schwartz J, Colicino E, Hou L, Vokonas PS, Hernandez DG, Singleton AB, Bandinelli S, Turner ST, Ware EB, Smith AK, Klengel T, Binder EB, Psaty BM, Taylor KD, Gharib SA, Swenson BR, Liang L, DeMeo DL, O’Connor GT, Herceg Z, Ressler KJ, Conneely KN, Sotoodehnia N, Kardia SLR, Melzer D, Baccarelli AA, van Meurs JBJ, Romieu I, Arnett DK, Ong KK, Liu Y, Waldenberger M, Deary IJ, Fornage M, Levy D, London SJ. Epigenetic signatures of cigarette smoking Circulation: Cardiovascular Genetics, (in press)
  31. Bakshi A, Zhu Z, Vinkhuyzen AAE, Hill WD, McRae AF, Visscher PM, Yang J. (2016) Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. Scientific Reports 6: 32894.
  32. Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai P-C, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S. (2016) DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging8: 1844.
  33. Pavlides JMW, Zhu Z, Gratten J, McRae AF, Wray NR, Yang J. (2016) Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine 8: 84.
  34. Kassam I, McRae AF (2016) The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes. Genome Biology 17: 169
  35. Mbarek H, Steinberg S, Nyholt DR, Gordon SD, Miller MB, McRae AF, Hottenga JJ, Day FR, Willemsen G, de Geus EJ, Davies GE, Martin HC, Penninx BW, Jansen R, McAloney K, Vink JM, Kaprio J, Plomin R, Spector TD, Magnusson PK, Reversade B, Harris RA, Aagaard K, Kristjansson RP, Olafsson I, Eyjolfsson GI, Sigurdardottir O, Iacono WG, Lambalk CB, Montgomery GW, McGue M, Ong KK, Perry JRB, Martin NG, Stefánsson H, Stefánsson K, Boomsma DI (2016) Identification of common genetic variants influencing spontaneous dizygotic twinning and female fertility. The American Journal of Human Genetics 98: 898-908
  36. Shakhbazov K, Powell JE, Hemani G, Henders AK, Martin NG, Visscher PM, Montgomery GW, McRae AF (2016) Shared genetic control of expression and methylation in peripheral blood. BMC Genomics 17: 278.
  37. Marioni RE, Harris SE, Shah S, McRae AF, von Zglinicki T, Martin-Ruiz C, Wray NR, Visscher PM, Deary IJ (2016) The epigenetic clock and telomere length are independently associated with chronological age and mortality. International Journal of Epidemiology 45:424-432.
  38. Tseng HW, Pitt ME, Glant TT, McRae AF, Kenna TJ, Brown MA, Pettit AR, Thomas GP (2016) Inflamation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes. Arthritis Research and Therapy 18: 35.
  39. Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EEM, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A, Steen VM, Hellard SL, Sundet K, Reinvang I, Espeseth T, Lundervold AJ, Giegling I, Konte B, Hartmann AM, Rujescu D, Roussos P, Giakoumaki S, Burdick KE, Bitsios P, Donohoe G, Corley RP, Visscher PM, Pendleton N, Malhotra AK, Neale BM, Lencz T, Keller MC (2015) Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry 21: 837-843
  40. Bui M, Benyamin B, Shah S, Henders AK, Martin NG, Montgomery GW, McRae AF (2015) Sharing a placenta is associated with a greater similarity in DNA methylation in monochorionic vs dichorionic twin pairs in blood at age 14. Twin Research and Human Genetics 18: 680-685.
  41. Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, Göring HHH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MMPJ, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SLR, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YDI, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, Franke L, Kettunen J, Visscher PM, Neely GG, Korstanje R, Hanson RL, Prokisch H, Ferrucci L, Esko T, Teumer A, van Meurs JBJ, Johnson AD (2015) The transcriptional landscape of age in human peripheral blood. Nature communications 6: 8570
  42. Marioni RE, Shah S, McRae AF, Ritchie SJ, Muniz-Terrera G, Harris SE, Gibson J, Redmond P, Cox SR, Pattie A, Corley J, Taylor A, Murphy L, Starr JM, Horvath S, Visscher PM, Wray NR, Deary IJ. (2015) The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology 44: 1388-1396
  43. Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM. (2015) Improving phenotypic prediction by combining genetic and epigenetic associations. The American Journal of Human Genetics 97: 75-85.
  44. Goldinger A, Shakhbazov K, Henders AK, McRae AF, Mongomery GW, Powell JE. (2015) Seasonal effects of gene expression. PLoS One 10: e0126995
  45. McRae AF, Visscher PM, Montgomery GW, Martin NG (2015) Large autosomal copy-number differences within unselected monozygotic twin pairs are rare. Twin Research and Human Genetics 18: 13-18.
  46. Marioni RE, Shah S, McRae AF*, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin M, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. (2015) DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology 16: 25. (* joint first authors)
  47. Shah S, McRae AF*, Marioni RE, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Starr JM, Wray NR, Deary IJ, Visscher PM (2014) Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research 24: 1725-1733. (* joint first authors)
  48. Hemani G, Shakhbazov K, Westra H-J, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. (2014) Hemani et al. reply. Nature 514: E5-E6.
  49. Thomson P, Parla JS, McRae AF*, Kramer M, Ranakrishnan K, Yao J, Soares DC, McCarthy S, Morris SW, Cardone L, Cass S, Ghiban E, Hennah W, Evans KL, Rebolini D, Millar JK, Harris SE, Starr JM, MacIntyre DJ, Generation Scotland, McIntosh AM, Watson JD, Deary IJ, Visscher PM, Blackwood DH, McCombie WR, Porteous DJ. (2013) 708 common and 2,010 rare DISC1 locus variants identified in 1,542 subjects: Analysis for association with psychiatric disorder and cognitive traits. Molecular Psychiatry 19: 668-675. (* joint first authors) PDF
  50. McRae AF, Powell JE, Henders AK, Bowdler L, Hemani G, Shah S, Painter JN, Martin NG, Visscher PM, Mongomery GW. (2014) Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biology 15: R73. PDF
  51. Hemani G, Shakhbazov K, Westra H-J, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. (2014) Detection and replication of epistasis influencing transcription in humans. Nature 508:249-253 PDF
  52. Derks EM, Ayub M, Chambert K, Del Favero J, Johnstone M, Macgregor S, Maclean A, McKechanie AG, McRae AF, Moran JL, Pickard BS, Purcell S, Sklar P, Stclair DM, Wray NR, Visscher PM, Blackwood DH. (2013) A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 162: 847-854. PDF
  53. Goldinger A, Henders AK, McRae AF, Martin NG, Gibson G, Montgomery GW, Visscher PM, Powell JE. (2013) Genetic and nongenetic variation revealed for the principal components of human gene expression. Genetics 195:1117-28. PDF
  54. McRae AF, Richter MM, Lind PA. (2013) Case-control association testing of common variants from sequencing of DNA pools. PLoS One 8:e65410. PDF
  55. Byrne EM, Carillo-Roa T, Henders AK, Bowdler L, McRae AF, Heath AC, Martin NG, Montgomery GW, Krause L, Wray NR. (2013) Monozygotic Twins affected with Major Depressive Disorder have greater variance in methylation than their unaffected co-twin. Translational Psychiatry 3: e269. PDF
  56. Powell JE, Henders AK, McRae AF, Kim J, Hemani G, Martin NG, Dermitzakis ET, Gibson G, Montgomery GW, Visscher PM. (2103) Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data. PLoS Genetics 9:e1003502. PDF
  57. McRae AF, Wright MJ, Hansell NK, Montgomery GW, Martin NG. (2013) No association between general cognitive ability and rare copy number variation. Behavior Genetics 43: 202-207. PDF
  58. Jablensky A, Angelicheva D, Donohoe GJ, Cruickshank M, Azmanov DN, Morris DW, McRae AF, Weickert CS, Carter KW, Chandler D, Alexandrov B, Usheva A, Morar B, Verbrugghe PL, Filipovska A, Rackham O, Bishop AR, Rasmussen KØ, Dragovic M, Cooper M, Phillips M, Badcock J, Bramon-Bosch E, Almeida OP, Flicker L, Gill M, Corvin A, MacGregor S, Kalaydjieva L. (2012) Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia. Molecular Psychiatry 17: 1328–1339. PDF
  59. Byrne EM, Johnson J, McRae AF, Nyholt DR, Medland SE, Gehrman PR, Heath AC, Madden PAF, Montgomery GW, Chenevix-Trench G, Martin NG. (2012) A genome-wide association study of caffeine-related sleep disturbance: Confirmation of a role for the adenosine receptor. Sleep 35: 967-975. PDF
  60. Powell JE, Henders AK, McRae AF, Wright MJ, Martin NG, Dermitzakis ET, Visscher PM, Montgomery GW. (2012) The Brisbane Systems Genetics Study: Genetical genomics meets complex trait genetic. PLoS ONE 7: e35430. PDF
  61. Powell JE, Henders AK, McRae AF, Wright MJ, Martin NG, Dermitzakis ET, Montgomery GW, Visscher PM. (2012) Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Research 22: 456-466. PDF
  62. Mosing MA, Medland SE, McRae AF, Landers G, Wright MJ, Martin NG. (2012) Genetic influences on life-span and its relationship to personality: A 16 year follow-up study of a sample of ageing twins. Psychosomatic Medicine 74: 16-22. PDF
  63. Luong HTT, Chaplin J, McRae AF, Medland SE, Willemsen G, Nyholt DR, Henders AK, Hoekstra C, Duffy DL, Martin NG, Boomsma DI, Montgomery GW, Painter JN. (2011) Variation in BMPR1B, TGFRB1 and BMPR2 and control of dizygotic twinning. Twin Research and Human Genetics 14: 408-16 PDF
  64. Larsson M, Duffy DL, Zhu G, Liu JZ, Macgregor S, McRae AF, Wright MJ, Sturm RA, Mackey DA, Mongomery GW, Martin NG, Medland SE. (2011) GWAS findings for human iris patterns: Associations with variants in genes that influence normal neuronal pattern development. American Journal of Human Genetics 89: 334-343. PDF
  65. Frank RAW, McRae AF*, Pocklington AJ, van de Lagemaat, LN, Navarro, P, Croning MDR, Komiyama NH, Armstrong JD, Finn RD, Malloy MP, MacLean AW, Harris SE, Starr JM, Bhaskar SS, Howard EK, Hunt SE, Coffey AJ, Ranganath V, Deloukas P, Rogers J, Muir WJ, Deary IJ, Blackwood DH, Visscher PM, Grant SGN. (2011) Clustered coding variants in the synaptic receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS ONE 6: e19011. (* joint first authors) PDF
  66. Ferreira MA, McRae AF, Medland SE, Nyholt DR, Gordon SD, Wright MJ, Henders AK, Madden PA, Visscher PM, Wray NR, Heath AC, Montgomery GW, Duffy DL, Martin NG. (2011) Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. European Journal of Human Genetics 19: 458-464. PDF
  67. Gratten J, Wilson AJ, McRae AF, Beraldi D, Visscher PM, Pemberton JM, Slate J. No evidence for warming climate theory of coat colour change in Soay sheep: a comment on Maloney et al. Biology Letters 6: 678-679 (2010) PDF
  68. Sommerlad S, McRae AF, McDonald B, Johnstone I, Cuttell L, Seddon JM, O’Leary CA. (2010) Congenital sensorineural deafness in Australian Stumpy-Tail Cattle Dogs is an autosomal recessive trait that maps to CFA10. PLoS ONE 5: e13364. PDF
  69. Liu JZ, McRae AF, Nyholt DR, Medland SE, Wray NR, Brown KM; AMFS Investigators, Hayward NK, Montgomery GW, Visscher PM, Martin NG, Macgregor S. (2010) A Versatile Gene-Based Test for Genome-wide Association Studies. American Journal of Human Genetics 87: 139-145. PDF
  70. Liu JZ, Medland SE, Wright MJ, Henders AK, Heath AC, Madden PA, Duncan A, Montgomery GW, Martin NG, McRae AF. (2010) Genome-wide association study of height and body mass index in Australian twin families. Twin Research and Human Genetics 13: 179-193. PDF
  71. Johnston SE, Beraldi D, McRae AF, Pemberton JM, Slate J. (2010) Horn type and horn length genes map to the same chromosomal region in Soay sheep. Heredity 104: 196-205. PDF
  72. Knight HM, Pickard BS, Maclean A, Malloy MP, Soares DC, McRae AF, Condie A, White A, Hawkins W, McGhee K, van Beck M, Macintyre D, Starr JM, Deary IJ, Visscher PM, Porteous DJ, Cannon RE, St Clair D, Muir WJ, Blackwood DHR. (2009) A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder and depression. American Journal of Human Genetics 85: 833-846. PDF
  73. Medland SE, Nyholt DR, Painter JN, McEvoy BP, McRae AF, Zhu G, Gordon SD, Wray NR, Ferreira MAR, Wright MJ, Henders AK, Campbell MJ, Duffy DL, Hansell NK, Macgregor S, Slutske WS, Heath AC, Montgomery GW, Martin NG. (2009) Common variants in the Trichohyalin gene are associated with straight hair in Europeans. American Journal of Human Genetics 85: 750-755. PDF
  74. Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Whitfield JB, Visscher PM, Montgomery GW. (2009) Family-based mitochondrial association study of traits related to type 2 diabetes and the metabolic syndrome in adolescents. Diabetologia 52: 2359-2368. PDF
  75. Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Wright MJ, Montgomery GW, Visscher PM. (2009) Association study of common mitochondrial variants and cognitive ability. Behavior Genetics 39: 504-512. PDF
  76. Keller MC, McRae AF, McGaughran JM, Visscher PM, Martin NG, Montgomery GW. (2009) Paternal isodisomy of Chromosome 2 with no apparent phenotypic effects detected using genomewide association data. American Journal of Medical Genetics Part A 149: 1823-1826. PDF
  77. McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas L, Ahmadi KR, Boomsma D, Willemsen G, Hottenga JJ, Pederson NL, Magnusson PKE, Ohm Kyvik K, Christensen K, Kaprio J, Heikkilä K, Palotie A, Widen E, Muilu J, Syvänen AC, Liljedahl U, Hardiman O, Cronin S, Peltonen L, Martin NG, Visscher PM. (2009) Geographical structure and differential natural selection amongst North European populations. Genome Research 19: 804-814. PDF
  78. Benyamin B, Visscher PM, McRae AF. (2009) Family-based genome-wide association studies. Pharmacogenomics 10: 181-190. PDF
  79. Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GHT, Wong AHC, Feldcamp LA, Virtanen C, Halfvarson J, Tysk C, McRae AF, Visscher PM, Montgomery GW, Gottesman II, Martin NG, Petronis A. (2009) DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics 41: 240-245. PDF
  80. Benyamin B, McRae AF*, Zhu G, Gordon S, Henders AK, Palotie A, Peltonen L, Martin NG, Montgomery GW, Whitfield JB, Visscher PM. (2009) Variants in TF and HFE explain ~40% of genetic variation in serum transferrin levels. American Journal of Human Genetics 85: 60-65. (* joint first authors) PDF
  81. Sved JA, McRae AF, Visscher PM. (2008) Divergence between human populations estimated from linkage disequilibrium. American Journal of Human Genetics 83: 737-743. PDF
  82. Middelberg RP, Gordon SD, Zhu G, McRae AF, Montgomery GW, Martin NG, Whitfield JB. (2008) Linkage and association analyses of longitudinally measured lipid phenotypes in adolescence. Twin Research and Human Genetics 11: 603-620. PDF
  83. Byrne EM, McRae AF, Zhao ZZ, Martin NG, Montgomery GW, Visscher PM. (2008) The use of common mitochondrial variants to detect and characterise population structure in the Australian population: Implications for genome-wide association studies. European Journal of Human Genetics 16: 1396-1403. PDF
  84. Keith JM, McRae AF, Duffy D, Mengersen K, Visscher PM. (2008) Calculation of IBD probabilities with dense SNP or sequence data. Genetic Epidemiology 32: 513-519. PDF
  85. McRae AF, Byrne EM, Zhao ZZ, Montgomery GW, Visscher PM. (2008) Power and SNP tagging in whole mitochondrial genome association studies. Genome Research 18: 911-917. PDF
  86. Gratten J, Wilson AJ, McRae AF, Beraldi D, Visscher PM, Pemberton JM, Slate J. (2008) A localized negative genetic correlation constrains microevolution of coal color in wild sheep. Science, 319: 318-320. PDF
  87. Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM. (2007) Mapping QTL underlying fitness-related traits in a free-living sheep population. Evolution 61: 1403-1416. PDF
  88. Gratten J, Beraldi D, Lowder DV, McRae AF, Visscher PM, Pemberton JM, Slate J. (2007) Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proceedings of the Royal Society B: Biological Sciences 274: 619-626. PDF
  89. McRae AF, Matigan NA, Vadlamudi L, Mulley JC, Mowry B, Martin NG, Berkovic SF, Hayward NK, Visscher PM. (2007) Replicated effects of sex and genotyping on gene expression in human lymphoblastoid cell lines. Human Molecular Genetics 16: 364-373. PDF
  90. Beraldi D, McRae AF, Gratten J, Pilkington JG, Slate J, Visscher PM, Pemberton JM. (2007) Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). International Journal for Parasitology 37: 121-129. PDF
  91. Anderson CA, McRae AF, Visscher PM. (2006) A simple linear regression method for QTL linkage analysis with censored observations. Genetics 173: 1735-1745. PDF
  92. Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM. (2006) Development of a linkage map and mapping of phenotypic polymorphisms in a free living population of Soay sheep (Ovis aries). Genetics 173: 1521-1537. PDF
  93. McRae AF, Beraldi D. (2006) Examination of a region showing linkage map discrepancies across sheep breeds. Mammalian Genome, 17: 346-353. PDF
  94. McRae AF, Pemberton JM, Visscher PM. (2005) Modeling linkage disequilibrium in natural populations: The example of the Soay sheep population of St. Kilda, Scotland. Genetics 171: 251-258. PDF
  95. McRae AF, Bishop SC, Walling GA, Wilson AD, Visscher PM. (2005) Mapping of multiple quantitative trait loci for growth and carcass traits in a complex commercial sheep pedigree. Animal Science 80: 135-142. PDF
  96. Campbell AW, Bain WE, McRae AF, Broad TE, Johnstone PD, Dodds KG, Veenvliet B, Greer GJ, Glass BC, Beattie AE, Jopson NB, McEwan JC. (2003) Bone density in sheep: Genetic variation and quantitative trait localization. Bone 33: 540-548. PDF
  97. McRae AF, McEwan JC, Dodds KG, Wilson T, Crawford AM, Slate J. (2002) Linkage disequilibrium in domestic sheep. Genetics 160: 1113-1122. PDF

Preprints

  • Tianye Jia, Congying Chu, Yun Liu, Jenny van Dongen, Nicola J Armstrong, Mark E Bastin, Tania Carrillo-Roa, Anouk den Braber, Mathew Harris, Rick Jansen, Jingyu Liu, Michelle Luciano, Anil P.S. Ori, Roberto Roiz Santianez, Barbara Ruggeri, Daniil Sarkisyan, Jean Shin, Kim Sungeun, Diana Tordesillas Gutierrez, Dennis van’t Ent, David Ames, Eric Artiges, Georgy Bakalkin, Tobias Banaschewski, Arun L.W. Bokde, Henry Brodaty, Uli Bromberg, Rachel Brouwer, Christian Buchel, Erin Burke Quinlan, Wiepke Cahn, Greig I. de Zubicaray, Tomas J. Ekstrom, Herta Flor, Juliane H. Frohner, Vincent Frouin, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Neda Jahanshad, Jiyang Jiang, View ORCID ProfileJohn B. Kwok, Nicholas G. Martin, Jean-Luc Martinot, Karen A. Mather, Katie L. McMahon, Allan F. McRae, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomas Paus, Luise Poustka, Philipp G. Samann, View ORCID ProfilePeter R. Schofield, Michael N. Smolka, Lachlan T. Strike, Jalmar Teeuw, Anbupalam Thalamuthu, Julian Trollor, Henrik Walter, Joanna M. Wardlaw, Wei Wen, Robert Whelan, Liana G. Apostolova, Elisabeth B. Binder, View ORCID ProfileDorret I. Boomsma, Vince Calhoun, Benedicto Crespo-Facorro, Ian J. Deary, Hilleke Hulshoff Pol, Roel A. Ophoff, Zdenka Pausova, Perminder S. Sachdev, View ORCID ProfileAndrew Saykin, Margaret J. Wright, Paul M. Thompson, Gunter Schumann, Sylvane Desrivieres (2018) Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. bioRxiv, 460444
  • Daniel Trejo Banos, Daniel L McCartney, Tom Battram, Gibran Hemani, Rosie M Walker, Stewart W Morris, Qian Zhang, David J Porteous, Allan F. McRae, Naomi R Wray, Peter M Visscher, Chris S Haley, Kathryn L Evans, Ian J Deary, Andrew M McIntosh, Riccardo E Marioni, Matthew R Robinson (2018) Bayesian reassessment of the epigenetic architecture of complex traits. bioRxiv, 450288
  • Futao Zhang, Wenhan Chen, Zhihong Zhu, Qian Zhang, Ian J. Deary, Naomi R. Wray, Peter M. Visscher, Allan F. McRae, Jian Yang (2018) OSCA: a tool for omic-data-based complex trait analysis. bioRxiv, 445163
  • Anna J Stevenson, Daniel L McCartney, Sarah E Harris, Adele M Taylor, Paul Redmond, John M Starr, Qian Zhang, Allan F McRae, Naomi R Wray, Tara L Spires-Jones, Barry W McColl, Andrew M McIntosh, Ian J Deary, Riccardo E Marioni (2018) Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing. bioRxiv, 397877
  • Julia Sidorenko, Irfahan Kassam, Kathryn Kemper, Jian Zeng, Luke Lloyd-Jones, Grant W. Montgomery, Greg Gibson, Andres Metspalu, Tonu Esko, Jian Yang, Allan F. McRae*, Peter M. Visscher (2018) The effect of X-linked dosage compensation on complex trait variation. bioRxiv, 433870 (* joint senior author)
  • Qian Zhang, Costanza Vallerga, Rosie Walker, Tian Lin, Anjali Henders, Grant Montgomery, Ji He, Dongsehng Fan, Javed Fowdar, Martin Kennedy, Toni Pitcher, John Pearson, Glenda Halliday, John Kwok, Ian Hickie, Simon Lewis, Tim Anderson, Peter Silburn, George Mellick, Sarah E Harris, Paul Redmond, Alison Murray, David Porteous, Christopher Haley, Kathryn Evans, Andrew McIntosh, Jian Yang, Jacob Gratten, Riccardo Marioni, Naomi Wray, Ian Deary, Allan F McRae*, Peter Visscher. (2018) Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing. bioRxiv, 327890 (* joint senior author)
  • Olivia KL Hamilton, Qian Zhang, Allan F McRae, Rosie M Walker, Stewart W Morris, Paul Redmond, Archie Campbell, Alison D Murray, David J Porteous, Kathryn L Evans, Andrew M McIntosh, Ian J Deary, Riccardo E Marioni (2018) An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936. bioRxiv, 278234

Book Chapters

  • McRae AF. (2017) Analysis of Genome-Wide Association Data. in Bioinformatics: Volume II: Structure, Function, and Applications pp 161-173

 
Last updated: Dec 2018