Research

Contact Details

Bancroft Centre, QIMR

Queensland Statistical Genetics (QSTAG),
Bancroft Building,
Queensland Institute of Medical Research,
Post Office, Royal Brisbane Hospital,
300 Herston Road
Brisbane 4029,
Australia

Email: allan.mcrae [at] qimr.edu.au
Phone: +61 7 3362 0190
Fax: +61 7 3362 0101

Brief C.V.

Research Officer, QIMR (Brisbane, Australia), 2006-present.
PhD, Universtiy of Edinburgh, 2006. THESIS
Commonwealth Scholarship Recipient, 2002-2005.
Research Associate, AgReseach (Invermay, New Zealand), 2002.
BSc (Hons), Statisics and Genetics, University of Otago, 2002.

Publications

  1. Knight HM, Pickard BS, Maclean A, Malloy MP, Soares DC, McRae AF, Condie A, White A, Hawkins W, McGhee K, van Beck M, Macintyre D, Starr JM, Deary IJ, Visscher PM, Porteous DJ, Cannon RE, St Clair D, Muir WJ, Blackwood DHR . A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder and depression. American Journal of Human Genetics (in press – accepted October 2009)
  2. Medland SE, Nyholt DR, Painter JN, McEvoy BP, McRae AF, Zhu G, Gordon SD, Wray NR, Ferreira MAR, Wright MJ, Henders AK, Campbell MJ, Duffy DL, Hansell NK, Macgregor S, Slutske WS, Heath AC, Montgomery GW, Martin NG . Common variants in the Trichohyalin gene are associated with straight hair in Europeans. American Journal of Human Genetics (in press – accepted October 2009) AOP
  3. Johnston SE, Beraldi D, McRae AF, Pemberton JM, Slate J. Gene mapping reveals a shared genetic basis for horn type variation in Soay sheep. Heredity (in press – accepted July 2009) AOP
  4. Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Whitfield JB, Visscher PM, Montgomery GW. Family-based mitochondrial association study of traits related to type 2 diabetes and the metabolic syndrome in adolescents. Diabetologia 52: 2359-2368 (2009) PDF
  5. Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Wright MJ, Montgomery GW, Visscher PM. Association study of common mitochondrial variants and cognitive ability. Behavior Genetics 39: 504-512 (2009) PDF
  6. Keller MC, McRae AF, McGaughran JM, Visscher PM, Martin NG, Montgomery GW. Paternal isodisomy of Chromosome 2 with no apparent phenotypic effects detected using genomewide association data. American Journal of Medical Genetics Part A 149: 1823-1826 (2009) PDF
  7. McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas L, Ahmadi KR, Boomsma D, Willemsen G, Hottenga JJ, Pederson NL, Magnusson PKE, Ohm Kyvik K, Christensen K, Kaprio J, Heikkilä K, Palotie A, Widen E, Muilu J, Syvänen AC, Liljedahl U, Hardiman O, Cronin S, Peltonen L, Martin NG, Visscher PM. Geographical structure and differential natural selection amongst North European populations. Genome Research 19: 804-814 (2009) PDF
  8. Benyamin B, Visscher PM, McRae AF. Family-based genome-wide association studies. Pharmacogenomics 10: 181-190 (2009) PDF
  9. Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GHT, Wong AHC, Feldcamp LA, Virtanen C, Halfvarson J, Tysk C, McRae AF, Visscher PM, Montgomery GW, Gottesman II, Martin NG, Petronis A. DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics 41: 240-245 (2009) PDF
  10. Benyamin B*, McRae AF*, Zhu G, Gordon S, Henders AK, Palotie A, Peltonen L, Martin NG, Montgomery GW, Whitfield JB, Visscher PM. Variants in TF and HFE explain ~40% of genetic variation in serum transferrin levels. American Journal of Human Genetics 85: 60-65 (2009) (* joint first authors) PDF
  11. Middelberg RP, Gordon SD, Zhu G, McRae AF, Montgomery GW, Martin NG, Whitfield JB. Linkage and association analyses of longitudinally measured lipid phenotypes in adolescence. Twin Research and Human Genetics 11: 603-620 (2008) PDF
  12. Sved JA, McRae AF, Visscher PM. Divergence between human populations estimated from linkage disequilibrium. American Journal of Human Genetics 83: 737-743 (2008) PDF
  13. Byrne EM, McRae AF, Zhao ZZ, Martin NG, Montgomery GW, Visscher PM. The use of common mitochondrial variants to detect and characterise population structure in the Australian population: Implications for genome-wide association studies. European Journal of Human Genetics 16: 1396-1403 (2008) PDF
  14. Keith JM, McRae AF, Duffy D, Mengersen K, Visscher PM. Calculation of IBD probabilities with dense SNP or sequence data. Genetic Epidemiology 32: 513-519 (2008) PDF
  15. McRae AF, Byrne EM, Zhao ZZ, Montgomery GW, Visscher PM. Power and SNP tagging in whole mitochondrial genome association studies. Genome Research 18: 911-917 (2008) PDF
  16. Gratten J, Wilson AJ, McRae AF, Beraldi D, Visscher PM, Pemberton JM, Slate J. A localized negative genetic correlation constrains microevolution of coal color in wild sheep. Science, 319: 318-320 (2008) PDF
  17. Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM. Mapping QTL underlying fitness-related traits in a free-living sheep population. Evolution 61: 1403-1416 (2007) PDF
  18. McRae AF, Matigan NA, Vadlamudi L, Mulley JC, Mowry B, Martin NG, Berkovic SF, Hayward NK, Visscher PM. Replicated effects of sex and genotyping on gene expression in human lymphoblastoid cell lines. Human Molecular Genetics 16: 364-373 (2007) PDF
  19. Gratten J, Beraldi D, Lowder DV, McRae AF, Visscher PM, Pemberton JM, Slate J. Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proceedings of the Royal Society B: Biological Sciences 274: 619-626 (2007) PDF
  20. Beraldi D, McRae AF, Gratten J, Pilkington JG, Slate J, Visscher PM, Pemberton JM. Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). International Journal for Parasitology 37: 121-129 (2007) PDF
  21. Anderson CA, McRae AF, Visscher PM. A simple linear regression method for QTL linkage analysis with censored observations. Genetics 173: 1735-1745 (2006) PDF
  22. Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM. Development of a linkage map and mapping of phenotypic polymorphisms in a free living population of Soay sheep (Ovis aries). Genetics 173: 1521-1537 (2006) PDF
  23. McRae AF, Beraldi D. Examination of a region showing linkage map discrepancies across sheep breeds. Mammalian Genome, 17: 346-353 (2006) PDF
  24. McRae AF, Pemberton JM, Visscher PM. Modeling linkage disequilibrium in natural populations: The example of the Soay sheep population of St. Kilda, Scotland. Genetics 171: 251-258 (2005) PDF
  25. McRae AF, Bishop SC, Walling GA, Wilson AD, Visscher PM. Mapping of multiple quantitative trait loci for growth and carcass traits in a complex commercial sheep pedigree. Animal Science 80: 135-142 (2005) PDF
  26. Campbell AW, Bain WE, McRae AF, Broad TE, Johnstone PD, Dodds KG, Veenvliet B, Greer GJ, Glass BC, Beattie AE, Jopson NB, McEwan JC. Bone density in sheep: Genetic variation and quantitative trait localization. Bone 33: 540-548 (2003) PDF
  27. McRae AF, McEwan JC, Dodds KG, Wilson T, Crawford AM, Slate J. Linkage disequilibrium in domestic sheep. Genetics 160: 1113-1122 (2002) PDF